What happened when I missed a dose - http://www.sjwinfo.org Forums
Topic Title: What happened when I missed a dose
| |  "What happened when I missed a dose"
, Mon 6 Oct 15:15
I accidentally missed one day of SJW recently. That evening I went out for a few drinks with a friend of mine. I felt fine the following morning, but by the evening I was extremely depressed. It was as bad as I've ever experienced it - I was close to tears for the entire evening. The following day was almost as bad. SJW has worked very well for me for the last few months, so it was a scary experience. Fortunately I quickly got back to normal.
Everything I've read seems to suggest that stopping SJW wouldn't cause such an immediate and extreme reaction, so I'm wondering whether it was just a freakish coincidence. Maybe the fact that I was drinking that evening had something to do with it. SJW seems to cushion me against the post-alcohol depression that I used to get occasionally, so perhaps it was the combination of missing a dose and drinking a bit too much. Though that wouldn't explain why it was so severe.
I'm still trying to work out whether it was:
a) A sign that I can't cope without the SJW yet.
b) A withdrawal symptom (seems unlikely, but I suppose it's a possibility).
c) A coincidence.
d) A kind of reverse placebo effect.
e) Caused by the alcohol.
Anybody have any thoughts or similar experiences to share?
Dan
Posts: 228 | | Registered: Sat 14 Dec 2002 17:8 |
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| | "Re(1):What happened when I missed a dose" , Wed 8 Oct 05:41
I too notice a decrease in anti depression after tiredness. I guess my body only has a certain reserve of the goody neurotransmitters and then after they are gone, depression sets in. Milk thistle really seems to increase my body's ability to manufacture and retain those goody neurotransmitters so I gather that anything that increases the load on the liver would make depression a more probable state.
Posts: 26 | | Registered: Mon 18 Aug 2003 14:41 |
| | "Re(1):What happened when I missed a dose" , Wed 8 Oct 05:09
I too am surprised at such a powerful reaction after missing one dose. I think as the other guys have said it was more a combination of things. However, SJW is a powerful herb that has been compared to the likes of prozac. My girlfriend and best friend are both on medical anti depressants, and I certainly know that when one of them has missed a dose it affects them grately. They feel dizzy, become anxious and feel down. Whether this is a pyscholical affect from 'expecting' symptoms to happen, who knows, but it wouldn't surprise me if a missed dose of SJW had the same powerful affects. Keep that chin up and good luck.
Posts: 2 | | Registered: Sun 28 Sep 2003 14:8 |
| | "Re(1):What happened when I missed a dose" , Wed 8 Oct 05:07
I too am surprised at such a powerful reaction after missing one dose. I think as the other guys have said it was more a combination of things. However, SJW is a powerful herb that has been compared to the likes of prozac. My girlfriend and best friend are both on medical anti depressants, and I certainly know that when one of them has missed a dose it affects them grately. They feel dizzy, become anxious and feel down. Whether this is a pyscholical affect from 'expecting' symptoms to happen, who knows, but it wouldn't surprise me if a missed dose of SJW had the same powerful affects. Keep that chin up and good luck.
Posts: 2 | | Registered: Sun 28 Sep 2003 14:8 |
| | "Re(1):What happened when I missed a dose" , Tue 7 Oct 14:23:
I've experienced this too on a couple of occasions and can't say that I've ever really managed ot get to the bottom of it. I have absolutely no doubt in my mind that alcohol acts as a depressant and I find that even if I have been taking SJW and then have an evening where I consume more than a few drinks I can certainly feel a tangible negative effect the following day.
I usually find it very difficult to reconcile the fact that I can be feeling great all of for instance Friday, go out in the evening and thoroughly enjoy myself with friends and then wake up on Saturday and whilst others would be smiling and thinking of what a wonderful evening they had, my mood will be through the floor!
I agree with what Sheephead says about tiredness - that has always been the main catalyst which causes a period of depression in me, but to comment on the rest of your bullet points I would have to guess that:
a) is possibly the case but would not have manifested itself to such a noticable degree after just one day wothout tablets and one evening in a pub - I remember the first time a couple of years back after I had been taking SJW for a few months and decided I no longer needed it, it took a good month before I felt sufficiently down to persuade myself that in fact I did still need it...you've been taking SJW for far longer than that, so I imagine that it would take even longer before you passed the 'apex' of the curve and started sliding down again.
b) I suppose that the above comments on this, but I know that personally I have had lots of day where I have either forgotten or simply not had the opportunity to take SJW and have never suffered any withdrawl, particularly after a day. Indeed on the two or three occassions when I have stopped SJW, I simply did so overnight and never really suffered any withdrawl at all.
c) Quite possibly the one - were you under any abnormal stress at the time, were you overly tired, had you been feeling down that week at all? - perhaps it's like getting a cold when you go on holiday in the summer - it's only when you wind-down that it strikes...perhaps the end of a hard week can elicit the same reaction?
d) By this I guess that you mean that you felt depressed because you consciously knew that you had missed a day, and then thought about the potential if unfeasible consequences and voila!...again unlikly but possible, I know that when I'm feeling down I can talk myself into just about anything and persuade myself that just about anything is true!
From another perspective, you say that you recovered very quickly which means that the SJW had in no way left your system...I think this points towards the coincidence/anomoly theory:
I suppose that you as a scientist have already realised that the thing to do would be to miss another day of SJW, try to recreate the same environment you lived in during that week, inflict the same level of stress upon yourself and then......... but I don't think that such extreme control experiments are required!!
Hope things are going OK!
David
PS Sorry about the length of this post and the (probably numerous) typing errors!!
[this message was edited by David on Tue 7 Oct 14:31]
Posts: 332 | | Registered: Sat 13 Oct 2001 17:39 |
| | "Re(1):What happened when I missed a dose" , Tue 7 Oct 01:29:
Dear Daniel,
To be honest, it was probably a combination of factors.
Like yourself, I am surprised that you suffered such a severe reaction after only one day off SJW.
I find that the one, single thing that causes my depressive symptoms to start creeping back is tiredness.
Although I like my ales, the one problem with drinking is that, in sufficient quantity, it can greatly exacerbate any normal tiredness caused by work, or whatever. This can lead to a sudden, unexpected 'crisis point'.
Not sure, but your reaction may have been triggered by a slight, but significant, drop in SJW followed by an untimely trip down the alehouse.
Sheephead.
[this message was edited by sheephead on Tue 7 Oct 06:27]
Posts: 49 | | Registered: Sun 29 Dec 2002 11:31 |
| | | "Re(2):What happened when I missed a dose" , Wed 8 Oct 05:37
I too notice a decrease in anti depression after tiredness. I guess my body only has a certain reserve of the goody neurotransmitters and then after they are gone, depression sets in. Milk thistle really seems to increase my body's ability to manufacture and retain those goody neurotransmitters so I gather that anything that increases the load on the liver would make depression a more probable state.
Posts: 26 | | Registered: Mon 18 Aug 2003 14:41 |
| | | "Re(3):What happened when I missed a dose" , Wed 8 Oct 15:01
Thanks for all your replies. Now that I think of it, I was tired that day so that could have had a lot to do with it. I know that SJW has a relatively long half-life, and most people report that it takes at least a couple of weeks for depression to return when they stop taking it, so it's unlikely that I would feel like I did after missing just one day. I don't think it was a complete coincidence though. It's more likely that missing that dose made me vulnerable to the effects of the alcohol and tiredness. The SJW always seemed to protect me against this before, so perhaps the slight drop caused by missing a dose was enough to take away that protection. It's strange that it was so severe, but it may have seemed that way because I was doing so well during the summer.
I'm completely recovered now and the whole experience has renewed my appreciation of what SJW has done for me, by reminding me of how I used to feel before I started taking it.
Thanks,
Dan
Posts: 229 | | Registered: Sat 14 Dec 2002 17:8 |
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