Topic Title: Re: Quit Paxil - 5hpt? Quality?
| | "Re: Quit Paxil - 5hpt? Quality?" , Sat 11 Aug 13:32
I have quit Paxil -- What a trip that was!! NOT good. I wanted to try either St. John's Wort or 5hpt. I did some research and the 5hpt sounds like what I would like to try first. I read one paper where there can be a problem with the quality of the product that can cause some awful disease (Sort of like why they took L-tryptophane off the market. Would appreciate any info.
Posts: 0 | | Registered: Sat 11 Aug 2001 13:27 | | |
| | "Re(1):Re: Quit Paxil - 5hpt? Quality?" , Tue 6 Aug 23:18
Hello. Saw an old post from August. You were on Paxil. And came off it. What symptoms did you have? I'm currantly slowly coming off Zoloft, now down to 12mg. a day and beginning to feel queezy in my stomach, some headaches, and depression and anxiety creeping back in to my body. I'm going to try SAM-e. What did you finally decide to do? What are you taking now and how are you doing? I did feel great on the Zoloft, been on it 2 years. But, 2 years is long enought and I want to try a safer alternative. Thanks. PAR
Pauline
Posts: 104 | | Registered: Wednesday 14 Mar 2001 10:59 |
| | "5-HTP and the Potential Danger Zone" , Mon 27 Aug 03:38
There has been some suggestion by the pharmaceutical industry that 5-HTP taken with B6 causes the natural decarboxylation reaction of turning the 5-HTP into Seratonin. The problem with this is that it happens before the 5-HTP has crossed what is known as the blood/brain barrier. This creates Seratonin in the bloodstream rather than in the brain. It is the extra Seratonin in the blood stream that is thought to cause not only harmless flushing (the heated feeling some of you describe) and diarrhea, but also problems with fibrosis of the endocardium and valves in the heart, which can cause heart failure. Someone else posted this link that explains in more chemical detail: http://yarchive.net/med/5-htp.html
The bottom line is that taking it with B6 could mean that you are just wasting the 5-HTP before it does you any good or that it may actually be causing you problems.
This makes sense even if you only think of this one small detail: They don't sell Seratonin itself, they sell the blood/brain barrier transportable precursor, 5-HTP.
Why would won't they just sell Seratonin?? Wouldn't it be easier to skip the middleman?
Seratonin cannot pass the barrier as it is not recognized by the amino acid transport system -- a good thing, because if it did it would not stay in your brain and the entire human race would be depressed. It would just float around in your bloodstream potentially causing the problems noted above and opening up the sellers to law suits.
I believe many of you are getting the benefits of 5-HTP, but if you are also taking B6 you may also be getting into trouble. Just something to consider as you move forward.
I too am desperate for happiness, but as Kelly frequently and wisely points out -- I should seek it in as informed a manner as I can.
Posts: 1 | | Registered: Sun 26 Aug 2001 17:13 |
| | | "Re(1):5-HTP and the Potential Danger Zone" , Mon 27 Aug 05:43
After reading the article you mentioned, it did give me a scare about taking the dosage of 5htp that I take on a daily basis. I take between 400 and 500 mg per day. Then I looked more closely at the article, it was written in 1996, and this website is just a collection of archive news articles, it also explains that medical information can get outdated quickly.
I then read some information from the book I usually fall back on http://www.smart-publications.com/books/5htp/toc.html , it mentions that "concerns related to the concomitant use of vitamin B6 and the promotion of heart muscle and valve fibrosis by 5-HTP seem to have no basis in fact. It is conceivable that these problems could arise if there were excess peripheral serotonin. But, since very little serotonin is produced from 5-HTP outside of the central nervous system, the danger seems remote at best."
I take Nature's way 5htp which include B6 and C, and it works great!!
Posts: 41 | | Registered: Wed 20 Jun 2001 6:19 |
| | "Re(1):Re: Quit Paxil - 5hpt? Quality?" , Wed 22 Aug 17:02
Check out this website http://www.smart-publications.com/books/5htp/toc.html I also went from paxil to 5htp and I now take between 400 and 500 mg per day split dosage.
Posts: 34 | | Registered: Wed 20 Jun 2001 6:19 |
| | | "Re(2):Re: Quit Paxil - 5hpt? Quality?" , Sat 16 Mar 11:43
Greetings. When you were on Paxil, did it work well for you in treating symptoms of anxiety and depression? Did you gain weight on it? And, how long have you been on 5-HTP? Is it working just as well as the Paxil did? How long once starting on 5-HTP, did it take to get the full effect for relief of symptoms and at what increment of dosage of 5-HTP did you notice a good effect for you? Thank you. Pauline [email protected]
Pauline
Posts: 63 | | Registered: Wednesday 14 Mar 2001 10:59 |
| | | "Progress" , Fri 31 Aug 16:55
I have to tell you I started taking the 5HTP 100 mg. about 3 weeks ago. I noticed a very strong difference the first day. I was having anxiety and depression after coming off of Paxil. It went away -- right away. I know this sounds "to good to be true." But, its the truth. I was spacy the first few days. I think I should have started out at 50mg. Did have some intestinal stuff. I plan to try to cut back to 50mg. Whatever is in this -- it must be what I need.
Posts: 1 | | Registered: Sat 11 Aug 2001 13:27 |
| | | "Re(1):Progress" , Sun 24 Feb 20:17
Hello. How long were you on Paxil for and what strength dose were you taking daily? Did it work well for you? Is the 5-HTP working just as well for you as did the Paxil? I've been on Zoloft (same family as Paxil) for over a year at a very low dose and it has worked so well for my depression and anxiety. I find myself even singing while I'm washing the dishes. I tried St. Johns wort in the past, but it upset my stomach terribly. But, not am slowly weaning off the Zoloft, wanting to try 5-HTP, hoping it will make me feel just a good. Already, I'm feeling a bit more depressed and some minor anxiety and sleeping problems, which is to be expected I guess coming off this, after being on it over a year. Did you get real sick coming off Paxil? Would you recommend me starting out at 50mg. 5-HTP, once I'm off the Zoloft? Thanks a bunch. Pauline
Pauline
Posts: 58 | | Registered: Wednesday 14 Mar 2001 10:59 |
| | | "Re(1):Progress" , Mon 3 Sep 16:48
If you can find a brand like Nature's way that is enteric coated you won't have the stomach problems anymore. The enteric coated tablets are not digested until they reach the small intestine. I've been taking nature's way 5htp for 2 years with no stomach upset.
It's great when you finally find something that works, isn't it?
Posts: 50 | | Registered: Wed 20 Jun 2001 6:19 |
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