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Rainier
2nd April, 2008, 05:17 PM
Scientific background:

Promising "second-generation" adaptogen Rhodiola rosea (Russian Rhodiola) is a perennial plant with red, pink, or yellowish flowers. It has no biological relation to the "common" rose, but due to its similar fragrance it has been used as a substitute for Attar of Roses. One of the greatest things Rhodiola does is enhance mental and physical performance. It has been widely used by Russian athletes and cosmonauts to increase energy. Rhodiola is cardio-protective, normalizing the heart rate immediately after intense exercise. It improves the nervous system and mental functions such as memory, by increasing blood-supply to the muscles and brain, and it also increases protein synthesis. Rhodiola rosea has extraordinary pharmacological properties as an anti-mutagen and anti-depressive agent. In this respect Rhodiola rosea is much more powerful than other adaptogens. In one study done by O.M. Duhan and colleagues, the anti-mutagenic activities of Panax Ginseng and of Rhodiola rosea were compared. It became clear that the extracts of Rhodiola rosea had a higher capacity to counteract gene mutations induced by various mutagens (up to about 90% inhibition in some cases). The anti-depressive and anti-stress activity of Golden root is higher than that of St. John's Wort, Ginkgo biloba and Panax Ginseng.

markiegloomie
4th April, 2008, 07:39 PM
RR is amazing, the best AD available IME. The only pharma. AD I think is safe to take is mirtazapine, and I would still only take this (again) if every herbal option and 5-HTP fail.

Rachelnutritionist
14th April, 2008, 07:11 PM
Just a word of warning about mirtazapine. i became physically addicted and had awful withdrawal symptoms trying to come off it. i wouldn't recommend it for this reason. I has to come off it incredibly slowly , much slower than my GP said. When i was getting the withdrawal ,he said it was my illness coming back !! The medical profession doesn't like to admit that ADs are addictive.

markiegloomie
15th April, 2008, 08:41 AM
Just a word of warning about mirtazapine. i became physically addicted and had awful withdrawal symptoms trying to come off it. i wouldn't recommend it for this reason. I has to come off it incredibly slowly , much slower than my GP said. When i was getting the withdrawal ,he said it was my illness coming back !! The medical profession doesn't like to admit that ADs are addictive.

You're right. I don't recommend mirtazapine until you've tried all herb and supplement options. Of all of the first-line antidepressants mirtazapine is the best IMO - but they're all bad really. I had bad withdrawal when I came off it too - I was having mild visual hallucinations, mild pain all over my body, insomnia, and was constantly crying for a few days.